Daniel Manrique-Castano

Neuroscientist / Data Scientists.

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Laboratory of Neurovascular Interactions

Université Laval,

Quebec, Canada

I am a neuroscientist focused on understanding glial reactivity following brain injury. While doing my doctoral studies at the International Graduate School of Neuroscience at the Ruhr-University Bochum, Germany, I realized that traditional analysis methodologies were not suitable to solve my research questions. Thus, I started to educate myself in statistical modeling using probabilistic approaches (Bayesian statistics) and developed a strong data science-based perspective. My current interests lies in unraveling the intricacies of brain scarring and recovery. I leverage a blend of modeling-based data analysis, machine learning, and image processing to dissect these complex processes.

In addition, my foray into data analysis has led to the development of unbiased, automated image analysis techniques using Python and machine learning. These approaches are particularly beneficial for researchers grappling with traditional, manual cell counting methods.

Finally, I am an ardent advocate for open and reproducible science. I firmly believe this approach is essential for maintaining quality control in scientific literature and ensuring effective oversight of scientific outputs. If my expertise aligns with your program’s goals, please feel free to contact me.

news

Apr 09, 2024 This website is still under construction. Please excuse the broken/misguided links.
Apr 08, 2024 I published a new article showing how to perform point pattern analysis to explore the distribution of brain cells.
Apr 06, 2024 I published a blog to illustrate the use of the “cumulative” family in brms to treat categorical variables in regression.
Mar 30, 2024 I published a blog depicting the use of Student-t distribution in data analysis.
Mar 07, 2024 I’ll start lecturing on research design and data management for the doctoral program in Applied and Behavioral Neuroscience at Universidad San Buenaventura, Bogotá (Colombia).

latest posts

selected publications

  1. MatBio
    Topological remodeling of cortical perineuronal nets in focal cerebral ischemia and mild hypoperfusion
    Egor Dzyubenko , Daniel Manrique-Castano, Christoph Kleinschnitz , and 2 more authors
    Matrix Biology, Dec 208